Submicroscopic and asymptomatic Plasmodium falciparum and Plasmodium vivax infections are common in western Thailand - molecular and serological evidence

Table 3 Serological markers associated with asymptomatic infection

PlasmoDB ID	ORF fragment	Protein name	Organism	AUC	MW U
PF3D7_0206800		merozoite surface protein 2 (MSP2)	P. falciparum	0.742	0.016
PF3D7_0703700	Exon 1 Segment 1	conserved Plasmodium protein, unknown function	P. falciparum	0.735	0.008
PVX_119695	Exon 3 of 3	hypothetical protein, conserved	P. vivax SaI1	0.725	0.013
PVX_085120	Exon 3 of 5 Segment 2	hypothetical protein, conserved	P. vivax SaI1	0.722	0.020
PF3D7_0806500	Exon 1 Segment 1	DnaJ protein, putative	P. falciparum	0.717	0.029
PF3D7_1348800	Exon 1 of 4	E1E2 ATPase, putative	P. falciparum	0.697	0.030

The intensity of antibody responses to these polypeptides was significantly higher in asymptomatic malaria cases when compared to symptomatic cases. AUC, area under the curve; MW U, Mann–Whitney U.

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