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Table 1 In vitro anti-malarial activities (IC 50 and IC 90 ) of 10 anti-malaria compounds against the P. falciparum NF54 cell bank parasites

From: Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

Compound Maximal concentration tested (nM) IC 50 (nM) IC 90 (nM)
Average (n = 2) Standard deviation (n = 2) Average (n = 2) Standard deviation (n = 2)
Artemether 50 5.9 1.7 9.9 2.4
Artesunate 50 3.3 0.2 6.0 0.4
Dihydroartemisinin 35 2.5 0.1 5.0 0.6
Atovaquone 25 0.22 0.06 1.3 0.5
Mefloquine 728 45 6 85 13
Piperaquine 200 19 6 28 9
Lumefantrine 800 118 14 318 166
Chloroquine 250 11.2 1.4 14.7 2.0
Pyrimethamine 50 0.57 0.04 1.28 0.15
Proguanil 200,000 292 20 1,335 504