Table 1 Amino acid substitutions in the K13 gene in parasites from the China-Myanmar border (n = 191)

N11Y*

1 (0.5)

K189T

3 (1.6)

E252Q

1 (0.5)

R255K

1 (0.5)

I352T*

1 (0.5)

I376V*

2 (1.0)

P441L

1 (0.5)

P443S*

1 (0.5)

F446I

52 (27.2)

N458Y

1 (0.5)

C469Y*

2 (1.0)

L492S*

1 (0.5)

F495L*

2 (1.0)

P574L

12 (6.3)

C580Y

3 (1.6)

A676D

2 (1.0)

H719N

2 (1.0)

In kelch domain

79 (41.3)

Total

88 (46.1)