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Table 1 Prevalence (% positive), 95% confidence intervals, and mean fluorescence intensity of IgG responses to Plasmodium vivax RALP1-Ecto and RALP1-Tr in sera from human P. vivax patients and healthy individuals

From: Antigenicity and immunogenicity of PvRALP1, a novel Plasmodium vivax rhoptry neck protein

RALP1 No. of patient samples ( n ) 95% CI b MFI (%) No. of healthy individuals ( n ) 95% CI MFI (%) P -value d
  Positive Negative Total (%) a    Positive Negative Total (%) c    
Ecto 66 46 112 (58.9) 49.67–67.6 14138 4 76 80 (5.0) 87.54–97.99 5032 p < 0.0001
Tr 62 50 112 (55.4) 46.13–64.23 8757 6 74 80 (7.5) 84.59–96.52 3047 p < 0.0001
  1. MFI = mean fluorescence intensity.
  2. aSensitivity: % positive in patient samples.
  3. bConfidence intervals.
  4. cSpecificity: % negative control healthy samples.
  5. dDifferences in the total IgG prevalence for each antigen between P. vivax patients and healthy individuals were calculated with Student’s t-test. P < 0.05 was considered significant.