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Table 3 Risk of treatment failure in six study sites adjusted for age and sex

From: Monitoring the efficacy of artemether-lumefantrine for the treatment of uncomplicated malaria in Malawian children

Characteristic PCR-corrected cure rate Hazard ratio 1 (95% CI) P value
Per protocol analysis    
Age group(months)    
6 - 12 86.5% (32/37) 1 -
13 - 24 91.1% (82/90) 0.79 (0.25, 2.46) 0.680
25 - 36 94.1% (48/51) 0.46 (0.11, 1.95) 0.289
37 - 59 93.7% (74/79) 0.50 (0.14, 1.76) 0.283
Sex    
Female 90.5% (114/126) 1  
Male 93.3% (125/134) 0.71 (0.30, 1.72) 0.457
Study site    
Karonga 98.0% (49/50) 1 -
Kawale 97.4% (38/39) 1.25 (0.08, 20.28) 0.873
Machinga 90.2% (37/41) 4.76 (0.52, 43.34) 0.166
Mangochi 97.4% (41/43) 2.08 (0.19, 23.16) 0.550
Nkhotakota 78.1% (32/41) 10.60 (1.33, 83.94) 0.025
Rumphi 91.3% (42/46) 4.33 (0.48, 39.03) 0.191
  1. 1Tested by Cox regression (95% Confidence Interval).