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Table 3 Risk of treatment failure in six study sites adjusted for age and sex

From: Monitoring the efficacy of artemether-lumefantrine for the treatment of uncomplicated malaria in Malawian children

Characteristic

PCR-corrected cure rate

Hazard ratio 1 (95% CI)

P value

Per protocol analysis

   

Age group(months)

   

6 - 12

86.5% (32/37)

1

-

13 - 24

91.1% (82/90)

0.79 (0.25, 2.46)

0.680

25 - 36

94.1% (48/51)

0.46 (0.11, 1.95)

0.289

37 - 59

93.7% (74/79)

0.50 (0.14, 1.76)

0.283

Sex

   

Female

90.5% (114/126)

1

 

Male

93.3% (125/134)

0.71 (0.30, 1.72)

0.457

Study site

   

Karonga

98.0% (49/50)

1

-

Kawale

97.4% (38/39)

1.25 (0.08, 20.28)

0.873

Machinga

90.2% (37/41)

4.76 (0.52, 43.34)

0.166

Mangochi

97.4% (41/43)

2.08 (0.19, 23.16)

0.550

Nkhotakota

78.1% (32/41)

10.60 (1.33, 83.94)

0.025

Rumphi

91.3% (42/46)

4.33 (0.48, 39.03)

0.191

  1. 1Tested by Cox regression (95% Confidence Interval).