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Table 3 Packed cell volume (PCV) of Plasmodium berghei-infected mice before and after the administration of the test extract of roots of Echinops kebericho

From: In vivo antiplasmodial and toxicological effect of crude ethanol extract of Echinops kebericho traditionally used in treatment of malaria in Ethiopia

Treatment groups

Before treatment

PCV (%) after treatment

% change

Negative control

50.34 ± 0.93

40.68 ± 0.91

−19.12 ± 0.14

200 mg/kg EKM

52.78 ± 1.58

50.34 ± 1.51*

−4.62 ± 1.11

350 mg/kg EKM

53.26 ± 1.52

52.34 ± 1.50*

−1.73 ± 1.15

500 mg/kg EKM

51.73 ± 0.48

49.41 ± 0.64*

−4.48 ± 0.52

25 mg/kg CQ

50.40 ± 0.39

52.30 ± 0.45*

+3.77 ± 0.42

  1. Results are expressed as means ± S E M, n = 5. *P < 0.001 versus negative control