Table 4 Tabulation of hypothetical data on incidence by active case detection in high and low resistance clusters, showing loss of effectiveness of second intervention (IRS)
Insecticide resistance | Vector control | Incidence (cases per 1,000 person years) | Rate ratio (LLIN + IRS versus LLIN) | Change in effectiveness ratio (high versus low resistance) |
|---|---|---|---|---|
Low | LLIN | 100 | 1 | |
LLIN + IRS | 40 | 0.4 | 1 | |
High | LLIN | 100 | 1 | |
LLIN + IRS | 80 | 0.8 | 2.0 [95% CI 1.1–5.0; p = 0.04] |