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Table 1 Effect of Vernonia amygdalina leaf extracts on Plasmodium berghei gametocyte densities

From: Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds

Treatment groups

Experimenta

Microgametocytes per 2,500 IRBCs (95% CI)

Macrogametocyte per 2,500 IRBCs (95% CI)

Ver-EtOH

1

6.7 (5.4–8.0)

40.3 (35.9–44.7)

2

6.8 (5.6–8.0)

38.4 (32–44.8)

Ver-H2O

1

5.5 (4.9–6.1)

25.5 (22.8–28.2)*

2

5.3 (4.9–5.7)*

23.3 (20.7–26.0)*

Control

1

7.2 (5.1–9.3)

48 (34.7–61.3)

2

8.5 (6.1–10.9)

41.7 (33.6–49.7)

  1. Data are presented as arithmetic means with 95% confidence intervals (95% CI).
  2. IRBCs infected red blood cells, Ver-EtOH ethanolic V. amygdalina leaf extract, Ver-H 2 O aqueous V. amygdalina leaf extract *p < 0.05 with respect to their control.
  3. aNumbers 1 and 2 refer to the two replicate experiments each involving treatment and control groups consisting of six mice each.