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Table 5 Demographic characteristics of the participants

From: Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

Variable

Group 1

2,500 PfSPZ in 10 µL IM

N = 6

Median

(Min; max)

Group 2

2,500 PfSPZ in 50 µL IM

N = 6

Median

(Min; max)

Group 3

2,500 PfSPZ in 250 µL IM

N = 6

Median

(Min; max)

Group 4

3,200 PfSPZ in 500 µL DVI

N = 6

Median

(Min; max)

Group 5

25,000 PfSPZ in 10 µL IM

N = 6

Median

(Min; max)

Group 6

75,000 PfSPZ in 10 µL IM

N = 6

Median

(Min; max)

Total

N = 36

Median

(Min; max)

Age (years)

33

26

30

29

22

25

26

(21; 41)

(21; 32)

(24; 35)

(19; 40)

(20; 25)

(20; 32)

(19; 41)

Weight (Kg)

63

67

80

61

60

54

63

(58; 86)

(51; 79)

(58; 93)

(54; 73)

(51; 70)

(52; 79)

(51; 93)

Height (m)

1.71

1.71

1.74

1.69

1.7

1.64

1.7

(1.68; 1.75)

(1.65; 1.86)

(1.63; 1.85)

(1.59; 1.72)

(1.56; 1.75)

(1.60; 1.84)

(1.56; 1.86)

BMI (kg/m2)

22

21.5

26.2

22.8

21.3

20.3

22

(20.1; 28.1)

(18.0; 25.8)

(21.9; 30.7)

(19.1; 24.8)

(19.9; 22.8)

(19.4; 23.5)

(18.0; 30.7)

Sex

       

 Female

2 (33%)

3 (50%)

1 (17%)

4 (67%)

5 (83%)

5 (83%)

20 (56%)

 Male

4 (67%)

3 (50%)

5 (83%)

2 (33%)

1 (17%)

1 (17%)

16 (44%)

  1. kg kilogram, m meter, BMI body mass index, Min minimum value of the range, Max maximum value of the range.