Anti-parasitic effects of extract or fraction C of Agaricus blazei. a Parasitaemia, b survival and c body weight of mice infected with untreated pRBCs or treated during 1 h with A. blazei water extract or fraction C (500 μg/mL) in vitro. Neurologic signs of CM appeared on days 6–12 (shaded area), with death occurring 24–48 h after onset. Parasitaemia and body weight values are expressed as mean ± SD of 4 mice per group. #
p < 0.001, log-rank test and *p < 0.05, ANOVA followed Bonferroni’s test.