Genetic diversity of Plasmodium falciparum isolates from Baka Pygmies and their Bantu neighbours in the north of Gabon

Mvé-Ondo, Bertrand; Nkoghe, Dieudonné; Arnathau, Céline; Rougeron, Virginie; Bisvigou, Ulrich; Mouele, Lauriane Yacka; Boundenga, Larson; Durand, Patrick; Elguero, Eric; Lemmers, Simone; Délicat-Loembet, Lucrèce M.; Diamella-Moukodoum, Nancy; Paupy, Christophe; Renaud, François; Prugnolle, Franck; Ollomo, Benjamin

doi:10.1186/s12936-015-0862-5

Table 3 Pairwise F _ST estimates (θ) measured between each pair of populations

From: Genetic diversity of Plasmodium falciparum isolates from Baka Pygmies and their Bantu neighbours in the north of Gabon

	Group	Village	Isolated Pygmy villages	Mixed villages								Forestry Villages
			Pygmies	Pygmies	Pygmies	Pygmies	Bantus	Pygmies	Bantus	Pygmies	Bantus	Bantus	Bantus	Bantus
			Etho	Doumassi	Esseng	Mimbang	Mimbang	NkokAkom	NkokAkom	Zangaville	Zangaville	Bordamure	STIBG	TTIB
Microsatellites
Isolated Pygmy villages	Pygmies	Bitouga	−0.0256	−0.0101	−0.0033	−0.0068	−0.0016	−0.0005	−0.039	0.0075	−0.0217	0.0075	0.0025	−0.0017
Isolated Pygmy villages	Pygmies	Etho		−0.0138	−0.0168	0.0162	−0.0135	−0.0175	−0.033	−0.0117	−0.0212	0.008	0.0045	−0.0073
Mixed villages	Pygmies	Doumassi			−0.0069	−0.0175	0.0116	−0.0035	−0.0188	0.0392	−0.0301	0.0277	0.0058	0.02
	Pygmies	Esseng				−0.0022	0.0146	0.0164	−0.0166	−0.0202	−0.0138	0.0151	0.0113	0.0141
	Pygmies	Mimbang					−0.0015	0.0056	−0.0233	0.0057	0.0037	0.0164	0	0.0228
	Bantus	Mimbang						−0.0036	−0.0046	−0.0232	0.0156	0.0563	0.0142	0.0319
	Pygmies	NkokAkom							−0.02	0.0204	0.0163	0.0167	0.025	0.0139
	Bantus	NkokAkom								−0.0431	−0.0202	−0.0281	−0.0204	−0.0311
	Pygmies	Zangaville									−0.0277	0	−0.0065	−0.007
	Bantus	Zangaville										0.0025	−0.0087	−0.001
Forestry villages	Bantus	Bordamure											0.0144	0.0054
Forestry villages	Bantus	STIBG												0.01
Candidate genes
Isolated Pygmy villages	Pygmies	Bitouga	−0.0417	0.0421	0.1063	0.1041	0.1398	0.0372	0.2664*	0.149	0.1301	0.1632	0.1509*	0.1428
Isolated Pygmy villages	Pygmies	Etho		0.0027	0.0795	0.0244	0.1629	0.0272	0.2818	0.0324	0.0543	0.1335	0.1627*	0.1245
Mixed villages	Pygmies	Doumassi			0.0469	−0.0436	0.0255	−0.064	0.1047	−0.0423	−0.0001	0.0128	0.114*	0.0194
	Pygmies	Esseng				0.1123	0.1308	0.1079	0.2229*	−0.0417	0.0472	0.065	0.0752	0.1047*
	Pygmies	Mimbang					0.0236	−0.1455	0.0874	0.0718	−0.0164	0.0557	0.0987	0.0616
	Bantus	Mimbang						−0.0626	0.0374	0.0465	0.064	0.088	0.0498	0.0471
	Pygmies	NkokAkom							0.0754	0.1014	0.0076	0.0031	0.0273	0.0278
	Bantus	NkokAkom								0.2069	0.1619	0.1916	0.1838*	0.1617
	Pygmies	Zangaville									−0.0312	−0.0239	0.1373	−0.0645
	Bantus	Zangaville										0.0622	0.1055	0.0735
Forestry villages	Bantus	Bordamure											0.1085	0.0272
Forestry villages	Bantus	STIBG												0.1612*

Values in italics are F _ST values obtained within mixed villages between P. falciparum from Pygmies and Bantus
* P-value <0.05 (after Bonferroni correction)

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