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Table 4 Clinical adverse events in the per protocol population

From: Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study

  ASAQ (number of patients) AL (number of patients) P
D0 D1 D2 D3 D7 Total % D0 D1 D2 D3 D7 Total %
Adverse effects 129 125 123 119 114   133 132 130 125 126   
Fatigue 2 18 19 25 1 65 10.7 3 14 12 5 4 38 5.9 0.02
Anorexia 3 1 1 2 2 9 1.5 0 1 1 2 1 5 0.8 0.2
Vomiting 8 10 4 4 2 28 4.6 11 9 5 0 1 26 4.0 0.6
Abdominal pain 3 6 4 4 2 19 3.1 2 2 2 3 5 14 2.2 0.3
Diarrhoea 2 3 4 0 2 11 1.8 9 2 1 0 0 12 1.9 0.9
Nausea 0 3 1 2 0 6 1 0 0 1 0 1 2 0.3 0.2
Headache 3 3 1 0 2 9 1.5 0 2 2 2 2 8 1.2 0.7
Jaundice 0 1 0 2 4 7 1.1 1 0 0 1 1 3 0.5 0.3
Dizziness 0 1 3 3 0 7 1.1 0 0 1 1 0 2 0.3 0.1
Pruritus 0 0 2 1 1 4 0.7 0 0 1 0 0 1 0.2 0.3
Rashes 0 0 0 0 1 1 0.2 0 0 0 0 0 0 0
  1. ASAQ artesunate-amodiaquine, AL artemether-lumefantrine