Table 5 Accuracy indices of the RDTs (HRP-2 and pLDH) bands compared with PCR to detect P. falciparum
| Â | Carestart | First Response | Parascreen | SD Bioline |
|---|---|---|---|---|
PCR as reference test | ||||
TP, FP | 12, 16 | 16, 14 | 14, 18 | 14, 16 |
FN, TN | 27, 879 | 23, 881 | 25, 887 | 25, 879 |
Sensitivity (95 % CI) | 30.7 (17.5–47.7) | 41.0 (25.9–57.8) | 35.8 (21.6–52.8) | 35.8 (21.6–52.8) |
Specificity (95 % CI) | 98.2 (97.0–98.9) | 98.4 (97.3–99.1) | 97.9 (96.7–98.7) | 98.2 (97.0–98.9) |
PPV (95 % CI) | 42.8 (25.0–62.5) | 53.3 (34.6–71.2) | 43.7 (26.8–62.1) | 46.6 (28.7–65.3) |
NPV (95 % CI) | 97.0 (95.6–97.9) | 97.4 (96.1–98.3) | 97.2 (95.8–98.1) | 97.2 (95.8–98.1) |
LR positive (95 % CI) | 17.2 (8.7–33.8) | 26.2 (13.8–49.8) | 17.8 (9.6–33.1) | 20.1 (10.6–38.1) |
LR negative (95 % CI) | 0.7 (0.44–1.28) | 0.59 (0.46–0.78) | 0.65 (0.52–0.83) | 0.65 (0.52–0.82) |
DOR (95 % CI) | 24.5 (9.7–61.2) | 44.4 (17.8–108.9) | 27.3 (11.3–65.6) | 30.9 (12.5–75.5) |