Table 1 Clinical and paraclinical baseline characteristics on admission
Regimens | p value | |||||
|---|---|---|---|---|---|---|
ARTES (n = 59) | QLD (n = 57) | QNLD3 (n = 62) | QNLD2 (n = 60) | Total (n = 238) | ||
Age (months), mean ± SD | 27.8 ± 23.0 | 34.0 ± 28.6 | 34.0 ± 28.5 | 38.0 ± 25.2 | 33.1 ± 24.6 | 0.08 |
Sex | ||||||
Female | 33 (55.9 %) | 32 (56.1 %) | 34 (54.8 %) | 26 (43.3 %) | 125 (52.5 %) | 0.43 |
Male | 26 (44.1 %) | 25 (43.9 %) | 28 (45.2 %) | 34 (56.7 %) | 113 (47.5 %) | |
Weight (kg), mean ± SD | 12.6 ± 5.6 | 13.2 ± 4.7 | 12.7 ± 4.5 | 14.8 ± 7.4 | 13.3 ± 5.7 | 0.18 |
Temperature (°C), mean ± SD | 39.3 ± 0.92 | 39.2 ± 0.92 | 39.3 ± 0.93 | 39.7 ± 0.86 | 39.3 ± 0.91 | 0.09 |
Heart rate (bpm), mean ± SD | 143.4 ± 18.1 | 145.6 ± 17.5 | 140.1 ± 17.6 | 141.9 ± 18.0 | 142.7 ± 17.2 | 0.29 |
Respiratory rate (cpm), mean ± SD | 44.3 ± 11.2 | 40.6 ± 9.7 | 40.3 ± 9.7 | 39.9 ± 8.6 | 41.3 ± 9.9 | 0.19 |
Coma depth (BCS), median | 2 (n = 3) | 2 (n = 6) | 3 (n = 4) | 2 (n = 4) | 2 (n = 17) | 0.48 |
Parasitaemia (parasites/µl), geometric mean (range) | 36,450 (0–306,400) | 40,311 (0–286,090) | 34,479 (0–284,000) | 35,564 (0–287,520) | 36,640 (0–306,400) | 0.87 |
Packed cell volume (%), mean ± SD | 19.7 ± 7.4 | 21.0 ± 7.7 | 22.6 ± 6.9 | 20.3 ± 6.7 | 20.9 ± 7.2 | 0.15 |
Blood glucose (g/l), mean ± SD | 1.03 ± 0.22 | 1.12 ± 0.29 | 1.06 ± 0.25 | 1.01 ± 0.20 | 1.05 ± 0.24 | 0.11 |
White blood cells (number/mm3), median (quartiles) | 8000 (4200–23,200) | 9400 (4900–26,800) | 9600 (4800–19,000) | 8650 (4500–22,800) | 8700 (4200–26,800) | 0.53 |