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Table 1 Clinical and paraclinical baseline characteristics on admission

From: A randomized trial of the efficacy of artesunate and three quinine regimens in the treatment of severe malaria in children at the Ebolowa Regional Hospital, Cameroon

  Regimens p value
ARTES (n = 59) QLD (n = 57) QNLD3 (n = 62) QNLD2 (n = 60) Total (n = 238)
Age (months), mean ± SD 27.8 ± 23.0 34.0 ± 28.6 34.0 ± 28.5 38.0 ± 25.2 33.1 ± 24.6 0.08
Sex
 Female 33 (55.9 %) 32 (56.1 %) 34 (54.8 %) 26 (43.3 %) 125 (52.5 %) 0.43
 Male 26 (44.1 %) 25 (43.9 %) 28 (45.2 %) 34 (56.7 %) 113 (47.5 %)
Weight (kg), mean ± SD 12.6 ± 5.6 13.2 ± 4.7 12.7 ± 4.5 14.8 ± 7.4 13.3 ± 5.7 0.18
Temperature (°C), mean ± SD 39.3 ± 0.92 39.2 ± 0.92 39.3 ± 0.93 39.7 ± 0.86 39.3 ± 0.91 0.09
Heart rate (bpm), mean ± SD 143.4 ± 18.1 145.6 ± 17.5 140.1 ± 17.6 141.9 ± 18.0 142.7 ± 17.2 0.29
Respiratory rate (cpm), mean ± SD 44.3 ± 11.2 40.6 ± 9.7 40.3 ± 9.7 39.9 ± 8.6 41.3 ± 9.9 0.19
Coma depth (BCS), median 2 (n = 3) 2 (n = 6) 3 (n = 4) 2 (n = 4) 2 (n = 17) 0.48
Parasitaemia (parasites/µl), geometric mean (range) 36,450 (0–306,400) 40,311 (0–286,090) 34,479 (0–284,000) 35,564 (0–287,520) 36,640 (0–306,400) 0.87
Packed cell volume (%), mean ± SD 19.7 ± 7.4 21.0 ± 7.7 22.6 ± 6.9 20.3 ± 6.7 20.9 ± 7.2 0.15
Blood glucose (g/l), mean ± SD 1.03 ± 0.22 1.12 ± 0.29 1.06 ± 0.25 1.01 ± 0.20 1.05 ± 0.24 0.11
White blood cells (number/mm3), median (quartiles) 8000 (4200–23,200) 9400 (4900–26,800) 9600 (4800–19,000) 8650 (4500–22,800) 8700 (4200–26,800) 0.53