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Table 4 Effect of IPTsc on clinical malaria during the intervention period

From: Efficacy and safety of intermittent preventive treatment for malaria in schoolchildren: a systematic review

 

Study site

Drug regime

No of children

Incidence rate per 1000 PYAR

PE (95 % CI)

Dicko [23]

Kambila

SP (bimonthly)




2.7a

40.1 (17.9–56.4)

  

Control




4.5a

–

Barger Barger [25]

Kollé

SP + AS

91

488

67 (42–98)

  

AQ + AS

97

782

47 (32–67)

  

Placebo

96

1463

–

Nankabirwa [27]

Tororo

DP (monthly)

236

0.01

97 (87–98)

  

DP (three and five monthly)

234

0.34

0.00

  

Placebo

243

0.34

–

  1. PE protective effect, No number, SP sulfadoxine-pyrimethamine, SP + AQ sulfadoxine-pyrimethamine plus amodiaquine, SP + AS sulfadoxine-pyrimethamine plus artesunate, DP dihydroartemisinin-piperaquine, 
 data not available, PYAR person-year at risk
  2. a5–10 years sub-group