Skip to main content

Table 1 Comparison of proportion of multiple alleles (MA) and mean allele counts (MAC) of parasite populations in (a) Asembo, Gem and Karemo areas, 2007 survey and (b) Asembo area in 2001 and 2007 surveys

From: Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya

(a) Asembo (n = 57), Gem (n = 87), Karemo (n = 92)

p value <0.05

Locus

Area

% MA

MAC ± SE

% MA*

MAC*

Poly-α

Asembo

59.6 %

2.22 ± 0.17

0.92

0.28

Gem

57.0 %

2.08 ± 0.13

  

Karemo

59.8 %

1.92 ± 0.10

  

Pfg377

Asembo

37.5 %

1.45 ± 0.09

0.06

0.02

Gem

32.9 %

1.40 ± 0.06

  

Karemo

20.7 %

1.24 ± 0.05

  

PfPK2

Asembo

53.6 %

1.96 ± 0.15

0.01

0.01

Gem

45.8 %

1.87 ± 0.12

  

Karemo

28.1 %

1.33 ± 0.06

  

ADL

Asembo

46.9 %

1.70 ± 0.12

0.79

0.13

Gem

53.9 %

2.01 ± 0.15

  

Karemo

50.0 %

1.71 ± 0.09

  

EBP

Asembo

41.2 %

1.49 ± 0.08

0.50

0.76

Gem

31.3 %

1.41 ± 0.07

  

Karemo

36.8 %

1.45 ± 0.07

  

P195

Asembo

29.6 %

1.37 ± 0.08

0.00

0.01

Gem

22.2 %

1.27 ± 0.05

  

Karemo

51.7 %

1.58 ± 0.06

  

TAA60

Asembo

52.6 %

1.84 ± 0.13

0.75

0.41

Gem

45.9 %

1.69 ± 0.09

  

Karemo

46.0 %

1.64 ± 0.09

  

TAA109

Asembo

44.4 %

1.53 ± 0.08

0.50

0.64

Gem

35.8 %

1.62 ± 0.11

  

Karemo

44.0 %

1.68 ± 0.11

  

Overall

Asembo

87.7 %a

2.76 ± 0.16b

0.01

0.53

Gem

83.7 %a

2.55 ± 0.14b

  

Karemo

96.7 %a

2.68 ± 0.08b

  

(b) Locus

% MA

MAC ± SE

p values

Asembo 2001

Asembo 2007

Asembo 2001

Asembo 2007

% MA*

MAC*

Poly-α

71.6 %

59.6 %

2.40 ± 0.14

2.22 ± 0.17

0.11

0.19

Pfg377

52.8 %

37.5 %

1.67 ± 0.09

1.45 ± 0.09

0.06

0.08

PfPK2

47.3 %

53.6 %

1.74 ± 0.11

1.96 ± 0.15

0.30

0.37

ADL

50.0 %

46.9 %

1.54 ± 0.07

1.70 ± 0.12

0.44

0.58

EBP

61.1 %

41.2 %

2.10 ± 0.14

1.49 ± 0.08

0.02

0.01

P195

47.9 %

29.6 %

1.62 ± 0.09

1.37 ± 0.08

0.03

0.02

TAA60

59.5 %

52.6 %

1.96 ± 0.12

1.84 ± 0.13

0.27

0.24

TAA109

76.7 %

44.4 %

2.26 ± 0.12

1.53 ± 0.08

0.01

0.01

Overall

95.9 %a

87.7 %a

3.1 ± 0.12b

2.76 ± 0.16b

0.03

0.16

  1. Asembo, Gem and Karemo denotes years after introduction of ITNs; 10, 9 and 3 years, respectively
  2. Asembo 2001 (n = 74); Asembo 2007 (n = 56)
  3. % MA is the proportion infections with more than one allele in each locus while the MAC is the mean allele count with the respective standard error (SE) at each locus. The superscript a marks the overall proportion of infections with at least two alleles while the superscript b marks the overall mean of the highest number of allele count detected by any of the eight microsatellites.  % MA* and MAC* show the p values for the differences in the proportion of multiple alleles and mean allele counts between parasite populations from the three areas or between 2001 and 2007 surveys. Numbers highlighted in italics show significance levels <0.05