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Table 1 Comparison of proportion of multiple alleles (MA) and mean allele counts (MAC) of parasite populations in (a) Asembo, Gem and Karemo areas, 2007 survey and (b) Asembo area in 2001 and 2007 surveys

From: Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya

(a) Asembo (n = 57), Gem (n = 87), Karemo (n = 92) p value <0.05
Locus Area % MA MAC ± SE % MA* MAC*
Poly-α Asembo 59.6 % 2.22 ± 0.17 0.92 0.28
Gem 57.0 % 2.08 ± 0.13   
Karemo 59.8 % 1.92 ± 0.10   
Pfg377 Asembo 37.5 % 1.45 ± 0.09 0.06 0.02
Gem 32.9 % 1.40 ± 0.06   
Karemo 20.7 % 1.24 ± 0.05   
PfPK2 Asembo 53.6 % 1.96 ± 0.15 0.01 0.01
Gem 45.8 % 1.87 ± 0.12   
Karemo 28.1 % 1.33 ± 0.06   
ADL Asembo 46.9 % 1.70 ± 0.12 0.79 0.13
Gem 53.9 % 2.01 ± 0.15   
Karemo 50.0 % 1.71 ± 0.09   
EBP Asembo 41.2 % 1.49 ± 0.08 0.50 0.76
Gem 31.3 % 1.41 ± 0.07   
Karemo 36.8 % 1.45 ± 0.07   
P195 Asembo 29.6 % 1.37 ± 0.08 0.00 0.01
Gem 22.2 % 1.27 ± 0.05   
Karemo 51.7 % 1.58 ± 0.06   
TAA60 Asembo 52.6 % 1.84 ± 0.13 0.75 0.41
Gem 45.9 % 1.69 ± 0.09   
Karemo 46.0 % 1.64 ± 0.09   
TAA109 Asembo 44.4 % 1.53 ± 0.08 0.50 0.64
Gem 35.8 % 1.62 ± 0.11   
Karemo 44.0 % 1.68 ± 0.11   
Overall Asembo 87.7 %a 2.76 ± 0.16b 0.01 0.53
Gem 83.7 %a 2.55 ± 0.14b   
Karemo 96.7 %a 2.68 ± 0.08b   
(b) Locus % MA MAC ± SE p values
Asembo 2001 Asembo 2007 Asembo 2001 Asembo 2007 % MA* MAC*
Poly-α 71.6 % 59.6 % 2.40 ± 0.14 2.22 ± 0.17 0.11 0.19
Pfg377 52.8 % 37.5 % 1.67 ± 0.09 1.45 ± 0.09 0.06 0.08
PfPK2 47.3 % 53.6 % 1.74 ± 0.11 1.96 ± 0.15 0.30 0.37
ADL 50.0 % 46.9 % 1.54 ± 0.07 1.70 ± 0.12 0.44 0.58
EBP 61.1 % 41.2 % 2.10 ± 0.14 1.49 ± 0.08 0.02 0.01
P195 47.9 % 29.6 % 1.62 ± 0.09 1.37 ± 0.08 0.03 0.02
TAA60 59.5 % 52.6 % 1.96 ± 0.12 1.84 ± 0.13 0.27 0.24
TAA109 76.7 % 44.4 % 2.26 ± 0.12 1.53 ± 0.08 0.01 0.01
Overall 95.9 %a 87.7 %a 3.1 ± 0.12b 2.76 ± 0.16b 0.03 0.16
  1. Asembo, Gem and Karemo denotes years after introduction of ITNs; 10, 9 and 3 years, respectively
  2. Asembo 2001 (n = 74); Asembo 2007 (n = 56)
  3. % MA is the proportion infections with more than one allele in each locus while the MAC is the mean allele count with the respective standard error (SE) at each locus. The superscript a marks the overall proportion of infections with at least two alleles while the superscript b marks the overall mean of the highest number of allele count detected by any of the eight microsatellites.  % MA* and MAC* show the p values for the differences in the proportion of multiple alleles and mean allele counts between parasite populations from the three areas or between 2001 and 2007 surveys. Numbers highlighted in italics show significance levels <0.05