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Fig. 1 | Malaria Journal

Fig. 1

From: Potential public health impact of RTS,S malaria candidate vaccine in sub-Saharan Africa: a modelling study

Fig. 1

Model structure. M maternal protection, S susceptible, I infected (parasites emerging from the liver), C clinical disease episode, F severe disease episode and there are 6 levels of immunity with compartments S, I, C and F divided into 6 levels, R resistant, wm waning of maternal immunity, q probability of infection, s susceptibility to infection as a function of age, a probability of asymptomatic infection, r recovery rate from clinical disease, w waning rate of acquired immunity, r imm probability of developing full immunity. The model assumes two processes for acquisition of immunity, one process that protects against clinical malaria of any severity and a faster process that protects against severe malaria

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