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Table 3 Reported minimum steady-state values Css (min) for sulfamethoxazole (SMX) and trimethoprim (TMP) in previous studies

From: Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya

SMX (mg ml−1)

TMP (mg ml−1)

References

23.8

2.2

Present study

45.5a

2.2a

Kremers et al. [32]

35.6

1.5

Nowak et al. [31]

43.4

2.98

Kaplan et al. [30]

  1. aPlasma concentration converted to whole blood equivalents using blood/plasma ratio [39]
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Malaria Journal

ISSN: 1475-2875

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