Fig. 3

Longitudinal titers per species of infection and recurrence. a, c, e PfMSP titers (red); b, d, f: PvMSP1 titers (green). a Group 1 Pf titers in those seven volunteers with 2 or 3 P. falciparum or mixed P. falciparum/P. vivax infections; asterisk indicates the one volunteer with a new P. falciparum infection, not recrudescence. b Group 1 with 7 representative volunteers with P. vivax infections and P. vivax relapses only. c, d Titers in those with mono—P. falciparum infection followed by mono—P. vivax infection. e, f Titers in volunteers with mono—P. vivax infection followed by mono—P. falciparum infection. Study period is divided into approximately 2 week blocks along X axis. Geometric symbols indicate a clinic visit with serology blood draw. Those symbols in black are ones with a positive malaria blood smear. All diagnoses are by PCR-corrected blood smears