Skip to main content

Table 1 Binding partners for PfMDM2 and PfSWIB identified by biopanning of Plasmodium falciparum phage display libraries

From: Localization and interactions of Plasmodium falciparum SWIB/MDM2 homologues

Protein Identity of the binding partner (total number of amino acids) Amino acid sequence of binding domain (location in protein) Annotated domains within binding partner (location in protein) Region of the binding partner cloned into a His-tag vector
PfMDM2 PF3D7_1303400—conserved Plasmodium protein, unknown function
(1022)
KKKKKKEQTNEG
KKSVKGINKKDK
KRNSKVESKK
(505–538)
LisH domain
(8–34)
485–664
PfSWIB PF3D7_1356800—serine/threonine protein kinase, putative (ARK3)
(4044)
IYEKVNIDNDKV
KKKNLHSINDKK
IKINKTFMNEKD
MKGNNRKKYNTE
KRDNIKRNENDN
EKK
(788–847)
Ser/Thr protein kinase domain, putative
(1282–1528)
601–922
PfSWIB PF3D7_1003600—membrane skeletal protein IMC1-related (ALV5)
(281)
PKTIIQEKIIHV
PKNVTHIVEK
IVEVPEVKYIEK
IVEVPHIHYKNK
YVPK
(58–107)
Inner membrane complex protein domain
(58–153)
2–241