The risk of malaria in Ghanaian infants born to women managed in pregnancy with intermittent screening and treatment for malaria or intermittent preventive treatment with sulfadoxine/pyrimethamine

Table 2 Incidence of episodes of clinical malaria in study children (all episodes during passive surveillance)

Analysis population, Intervention group	Clinical malaria episodes	Person-years at risk	Incidence rates per year	Rate ratio^a (95 % CI)	p value*
ATP1, IPTp-SP	66	312.7	0.21	(Reference)	–
ATP1, ISTp-AL	73	308.5	0.24	0.94 (0.68, 1.33)	0.76
				Rate difference^a (95 % CI)	p value
		ATP1 (ISTp-AL– IPTp-SP)		0.029 (−0.053, 0.110)	0.49

Analysis population, Intervention group	No. ever had clinical malaria	No. children	Risk	Risk ratio^a (95 % CI)	p value*
ATP1, IPTp-SP	54	442	0.12	(Reference)	–
ATP1, ISTp-AL	68	440	0.15	1.27 (0.91, 1.76)	0.16
				Risk difference^a (95 % CI)	p value*
		ATP1 (ISTp-AL– IPTp-SP)		0.032 (−0.013,0.078)	0.17

IPTp-SP intermittent preventive treatment with sulfadoxine/pyrimethamine, ISTp-AL screening with a rapid diagnostic test (RDT) and treatment with artemether–lumefantrine, ATP1 primary analysis according to protocol
^* Two-sided p values
^aCovariates adjusted: for gender, socio-economic status, rural/urban residence location, irrigated area residence location, season, ITN use, age at visit, mother’s parasitaemia status on day of enrolment into the initial cohort, predelivery haemoglobin

ISSN: 1475-2875