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Table 3 Operational research topics identified and scored

From: Establishing research priorities for malaria elimination in the context of the emergency response to artemisinin resistance framework-the Cambodian approach

Thematic area Operational research topic Significance to malaria elimination Feasibility of scaling up nationwide Capacity Potential for funding Political will Urgency Total
1. Malaria epidemiology, surveillance and response MMP surveillance 3 2 2 3 3 3 16
Improved case surveillance 3 2 2 3 3 3 16
2. Malaria case management Asymptomatic cases and active surveillance and treatment 3 2 2 3 2 3 15
Feasibility of conducting DOTs for malaria cases 2 1 2 2 2 2 11
Use of microscopy as a primary method of laboratory confirmed diagnosis for malaria and establishment of a quality control program 2 3 2 1 1 2 11
3. Control of malaria vectors Vector Mapping—changing environment/epidemiology/variation across the country requires research into vectors (changing biting patters, life‐cycle, species, exo/endophilic, etc., insecticide resistance) 3 2 2 3 2 3 15
Bed net research—good national coverage, but how effective are they, are they protecting the most at risk populations (mobile migrant workers); sleeping behaviour of the net use net preference studies (hammocks, texture, colour) 3 3 2 1 1 3 13
4. Malaria behavioural issues How does DOTs change behaviour of the patients? Adherence of DOTs 2 3 3 2 3 2 15
How can we increase participatory village interventions? Active community involvement such as active case detection? 3 3 3 3 3 3 18
How can we increase the malaria education provided to patients by health facilities/VMWs? 3 3 3 2 3 3 7
How best to communicate with MMPs/forest goers? 3 2 2 3 2 3 15
5. Malaria clinical studies First line treatment drug efficacy (Pf, Pv) 3 3 3 2 3 2 16
New ACTs drug efficacy, Artesunate + Pyronaridine 3 1 3 3 1 3 14
Safety of primaquine (G6PD screening) 3 3 3 1 2 3 15
6. Other vector borne diseases (Dengue, NTDs, STHs) Dengue/Chikungunya surveillance and estimation of disease burden—lacking in adult and private sector 2 2 2 1 2 3 12
To determine a sustainable, effective and ecologically safe vector control measure for dengue control 3 1 1 1 1 3 10
NTD surveillance and estimation of disease burden—lacking in private sector N/ A N/A N/A N/A N/A N/A 0
NTD surveillance and vector control N/A N/A N/A N/A N/A N/A 0