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Table 2 Bi- and multivariate analyses of risk factors for developing a clinical malaria episode, including IRS the previous year in the household (179 cases, 1125 controls, 5 communes)

From: Effectiveness of malaria control interventions in Madagascar: a nationwide case–control survey

Variable

Category

N cases (%)

N controls (%)

Bivariate

Multivariate

Crude OR [95 %CI]

p

Adjusted OR [95 %CI]

p

IRS the previous year

No

92 (51.4)

778 (69.2)

0.50 [0.33–0.76]

0.001

0.49 [0.35–0.69]

<0.001

Yes

87 (48.6)

347 (30.8)

1.00

 

1.00

 

Age group

0–1 year

19 (10.6)

37 (3.3)

26.08 [12.00–56.71]

<0.001

20.76 [9.44–45.66]

<0.001

2–4 years

34 (19.0)

130 (11.6)

14.24 [6.12–33.16]

<0.001

12.85 [5.77–28.63]

<0.001

5–9 years

38 (21.2)

198 (17.6)

11.17 [5.39–23.16]

<0.001

9.69 [5.07–18.52]

<0.001

10–15 years

26 (14.5)

180 (16.0)

7.33 [2.08–25.90]

0.002

6.44 [2.03–20.41]

0.002

15–19 years

26 (14.5)

125 (11.1)

11.29 [3.57–35.67]

<0.001

10.03 [3.93–25.58]

<0.001

20–39 years

33 (18.4)

247 (22.0)

7.34 [2.77–19.43]

<0.001

6.45 [2.81–14.81]

<0.001

≥40 years

3 (1.7)

208 (18.5)

1.00

 

1.00

 

Sex

Male

98 (54.7)

476 (42.3)

1.00

 

1.00

 

Female

81 (45.3)

649 (57.7)

0.59 [0.52–0.66]

<0.001

0.65 [0.55–0.78]

<0.001

Transmission pattern

Fringe

55 (30.7)

219 (19.5)

1.00

 

1.00

 

West

118 (65.9)

697 (62.0)

0.61 [0.25–1.47]

0.269

1.50 [0.71–3.14]

0.288

South

6 (3.4)

209 (18.6)

0.11 [0.11–0.11]

<0.001

0.13 [0.12–0.14]

<0.001