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Table 2 Relationship between antibody levels and age

From: Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

Burkina Faso Ghana
Antibody Antigen Coefficient (95 % CI) p value Adjusted R2 Coefficient (95 % CI) p value Adjusted R2
IgG GLURP R2 6.69 (4.10, 10.91) <0.0001 0.14 2.82 (0.97, 8.23) 0.057 0.013
MSP1-hybrid 9.28 (4.75, 18.13) <0.0001 0.11 1.56 (4.10, 5.93) 0.51 0
AS202.11 2.23 (1.33, 4.28) 0.0037 0.021 0.86 (0.35, 2.14) 0.73 0
IgG1 GLURP R2 5.55 (2.91, 10.60) <0.0001 0.069 3.09 (1.00, 9.61) 0.051 0.014
MSP1-hybrid 2.08 (0.63, 6.83) 0.23 0.0013 0.71 (0.37, 1.36) 0.3 0.0004
IgG2 GLURP R2 10.37 (6.00, 17.94) <0.0001 0.16 2.39 (0.70, 8.12) 0.16 0.0047
MSP1-hybrid 21.88 (6.98, 68.57) <0.0001 0.072 1.00 (0.28, 3.66) 1 0
IgG3 GLURP R2 6.16 (4.02, 9.43) <0.0001 0.16 2.93 (1.20, 7.16) 0.019 0.021
MSP1-hybrid 2.81 (1.85, 4.26) <0.0001 0.061 3.09 (0.90, 1.06) 0.073 0.011
IgG4 GLURP R2 2.76 (1.62, 4.71) 0.00021 0.036 8.81 (0.94, 82.24) 0.056 0.013
MSP1-hybrid 1.88 (0.96, 3.68) 0.064 0.0069 3.42 (0.62, 18.77) 0.16 0.005
IgM GLURP R2 36.64 (14.83, 90.52) <0.0001 0.15 35 (5.01, 248.77) 0.0004 0.054
MSP1-hybrid 8.76 (3.18, 24.12) <0.0001 0.045 7.62 (1.05, 55.45) 0.045 0.015
AS202.11 3.60 (1.75, 7.41) 0.00055 0.031 6.86 (1.20, 3.93) 0.031 0.018
  1. Coefficient, 95 % confidence level (CI), p values and adjusted R2 values were calculated from univariate linear regression models