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Table 2 Comparison of microscopy, PCR genotyping and PfHRP-2 RDT results from the samples collected in April 2015

From: Plasmodium falciparum histidine rich protein-2 diversity and the implications for PfHRP 2: based malaria rapid diagnostic tests in Ghana

  PCR− PCR+ Microscopy− Microscopy+
Accra (RDT−) 31.6 % (12/38) 68.4 % (26/38) 47.4 % (18/38) 52.6 % (20/38)
Cape Coast (RDT−) 75 % (36/48) 25 % (12/48) 97.9 % (47/48) 2.1 % (1/48)
Accra (RDT+) 17.5 % (20/114) 82.5 % (94/114) 52.6 % (60/114) 47.4 % (54/114)
Cape Coast (RDT+) 73.1 % (19/26) 26.9 % (7/26) 96.2 % (25/26) 3.8 % (1/26)
  1. PCR− P. falciparum negative by PCR genotyping, PCR+ P. falciparum positive by PCR genotyping, microscopy− P. falciparum negative by microscopy, microscopy+ P. falciparum positive by microscopy, RDT+ sample produced a positive PfHRP-2 RDT test strip, RDT− sample produced a negative PfHRP-2 RDT test strip. A total of 114/152 and 38/152 positive and negative branded RDT kits respectively were collected from Accra and 26/74 positive and 48/74 negative branded RDT kits respectively were collected from Cape Coast