|
Year
|
2007–2010
|
2007–2010
|
2010–2011
|
2012–2014
|
|
No. of patients
|
59
|
61
|
100
|
83
|
|
Location (%)
|
|
Jalalabad
|
41 (69)
|
42 (69)
|
100 (100)
|
–
|
|
Takhar
|
6 (10)
|
5 (8)
|
–
|
–
|
|
Faryab
|
1 (2)
|
3 (5)
|
–
|
–
|
|
Kunar
|
11 (19)
|
11 (18)
|
–
|
83 (100)
|
|
Age (years) (median, range)
|
11 (2–52)
|
13 (1–70)
|
15.5 (3–55)
|
18 (1–74)
|
|
Gender male/female (ratio)
|
43/16 (2.7)
|
35/26 (1.3)
|
60/40 (1.5)
|
49/34 (1.4)
|
|
Body weight (kg) (median, range)
|
31 (8–87)
|
35 (7.5-85)
|
50 (10-72)
|
49 (10–75)
|
|
Median parasitaemia/µl (range)
|
6760 (1220–90,000)
|
7200 (900–62,160)
|
4680 (1000–95,000)
|
3220 (500–59,520)
|
|
No. of patients with gametocytes (%)
|
13 (22)
|
29 (48)
|
19 (19)
|
42 (51)
|
|
Mean axillary temp (°C) ± SD
|
37.9 ± 1.1
|
37.9 ± 1.0
|
38.4 ± 0.8
|
38.4 ± 0.9
|
|
Mean hemoglobin (g/dl) ± SD
|
11.2 ± 1.3
|
11.2 ± 1.4
|
11.50 ± 0.9
|
11.6 ± 1.9
|
|
Mean total drug dose (mg/kg) ± SD
|
|
Artemisinin derivative
|
6.7 ± 1.2 (DHA)
|
10.42 ± 1.9 (AS)
|
10.5 ± 2.0 (AS)
|
10.5 ± 2.4 (AS)
|
|
Partner drug
|
53.9 ± 9.3 (PIP)
|
27.35 ± 11.9 (SUL)
|
26.8 ± 5.0 (SUL)
|
27.3 ± 6.1 (SUL)
|
