A highly infectious Plasmodium yoelii parasite, bearing Plasmodium falciparum circumsporozoite protein

Malaria Journal

Table 3 Titration of the infectivity of PfCSP/Py Spz through the bite(s) of infected mosquitoes

	No. bites^a	Infected^b/total mice	% patent	PPP (days)^c
BALB/c mice	1	1/6	17 %	5
	5	6/6	100 %	4.2
	10	6/6	100 %	3.8

^a80 % of An. stephensi mosquito was infected with PfCSP/Py Spz in the salivary gland. Individual salivary glands were examined after each feed to ensure that mice received the indicated number of infected bites
^bInfection was defined as the observation of blood stage parasites in thin blood smears by Giemsa staining
^cPre-patent period (PPP), number of days after Spz inoculation until detection of blood stage parasites in Giemsa-stained thin blood smears

ISSN: 1475-2875