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Table 3 Estimates of DNA sequence polymorphism and tests of neutrality for pvs48/45

From: Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45

Country Total isolates SV sites PI sites # Mutations K H Hd ± SD π ± SD dN dS Reference
Mexico 15 0 2 2 0.441 2 0.221 ± 0.121 0.00033 ± 0.00033 0.00042 0.00000 This study
Honduras 12 3 2 5 1.128 4 0.445 ± 0.170 0.00123 ± 0.00094 0.00136 0.00077 This study
Colombia 60 3 4 7 1.929 9 0.841 ± 0.024 0.00188 ± 0.00073 0.00185 0.002 This study
Peru 24 1 2 3 0.372 3 0.218 ± 0.103 0.00034 ± 0.00046 0.00045 0.00000 This study
Brazil 13 2 1 3 0.59 4 0.526 ± 0.153 0.00058 ± 0.00062 0.00019 0.00194 This study
Latin America 124 3 5 8 1.228 11 0.610 ± 0.047 0.00168 ± 0.00087 0.00176 0.00151 This study
Myanmar 8 2 5 7 2.722 5 0.889 ± 0.071 0.00216 ± 0.00110 0.00282 0.0000 This study
Thailand 18 5 4 9 1.392 5 0.484 ± 0.138 0.00116 ± 0.00101 0.00103 0.00085 This study
South Korea 86 0 2 2 0.716 3 0.611 ± 0.026 0.00053 ± 0.00004 0.00069 0.00000 [17]
North Korea 46 2 7 9 1.987 5 0.0018 ± 0.042 0.00147 ± 0.00069 0.00029 0.00186 [18]
Worldwide 282 7 5 12 1.047 15 0.686 ± 0.00149 0.00173 ± 0.00149 0.00188 0.00149 This study
  1. SV singleton variable, PI parsimony informative, K average number of pair-wise differences, H number of haplotypes, Hd haplotype diversity, π observed average pair-wise nucleotide diversity, dN number of non-synonymous substitutions, dS number of synonymous substitutions