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Table 4 Potential antigenic determinants for the Pvs48/45

From: Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45

# Antigenic region AA start AA end Length Score Polymorphism Sequencea
1 4 19 16 1.235 None RQLANLLLVLSLLRGI
2 46 64 19 1.083 None GFKCNFSSKGVHNLEPILT
3 66 90 25 1.197 None KRSLVCSIYSYFIYDKIKLTIPKKI
4 99 109 11 1.129 None PEKCFQTVYTN
5 165 189 25 1.206 None ISNVKGRVALVQVNVLKYPHKITSI
6 220 237 18 1.228 None GELVVLACEKVDDKCFKK
7 242 304 63 1.154 K250N SPLSLYKSKKIVYHKNLSIFKAPVYVKSADVTAECSCNVDSTIYTLSLKPVYTKKLIHGCNFS
8 326 341 16 1.138 D335Y QITCSIELVDTSYNHL
9 347 361 15 1.167 E353Q PGEVLPECFFQVYQR
10 366 377 12 1.141 A376T LEPSKIVYLDAQ
11 394 404 11 1.152 None IVKIFGLVGSI
12 422 447 26 1.255 None YMSVKIAAGYFGFLAKIFILLIVLLL
  1. aItalics AA indicates Cysteine residues, whereas Bold italics AA represent the location of polymorphic sites