Fig. 1

Alignments of PfAKAL, P. yoelii AKAP18 (PyAKAP18g) and P. vivax ortholog (PVX080595) with Human AKAP18γ. In this box shade representation of the alignment, identical and similar residues are shaded respectively in black and grey. The residues involved in nucleotide binding are labeled with triangles above the alignment, the conserved residues interacting with the adenosine (red) and the residues interacting with the phosphate (black) moieties of 5′AMP in the human AKAP18 complex crystal structure. The human AKAP18 core domain is underlined with plain line