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Table 1 Participant characteristics at study enrollment in Machinga, Nkhotakota, and Karonga Districts, in Malawi, 2014 (n = 452)

From: In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falciparum malaria in Malawi, 2014

Characteristic AL ASAQ
Total (n = 338) Site Total (n = 114)
Machinga (n = 112) Nkhotakota (n = 113) Karonga (n = 113)
Age, months (median, range)*, † 31 (6, 58) 35 (7, 58) 27 (6, 57) 34 (6, 57) 38 (9, 59)
Male, n (%)* 176 (52.1) 67 (59.8) 49 (43.4) 60 (53.1) 45 (39.5)
Participant slept under ITN previous night, n (%)†, a 269 (81.5) 101 (91) 70 (64.2) 98 (89.1) 92 (84.4)
Weight (kg) (mean, SD) 11.3 (3.6) 11.9 (3.1) 11.3 (2.2) 10.7 (4.8) 11.7 (3.4)
Haemoglobin (g/dL) (mean, SD) 9.8 (2.3) 9.4 (3.2) 9.7 (1.8) 10.2 (1.5) 10.0 (1.9)
Anaemia (Hb ≤11.0 g/dL) 264 (78.1) 99 (88.4) 87 (77) 78 (69) 84 (73.7)
Parasitaemia (parasites/μL) (geometric mean, range)†, b 35,512 (1100, 394,400) 25,700 (1100, 198,000) 39,171 (1393, 394,400) 44,361 (2066, 265,750) 30,882 (1019, 274,908)
  1. All participants were eligible for enrollment based on initial parasitaemia (1000–200,000 parasites/μL); however, 26 (6.1 %) participants had parasitaemia higher than 200,000 parasites/μL according to slide reviews done after study completion
  2. * Significant difference between study arms (p < 0.05); significant difference between study sites (p < 0.05)
  3. aInsecticide-treated bed net
  4. bAsexual parasitaemia