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Table 3 Summary of IC50-values

From: Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

SGM assay Strain P1 P50
3D7
IC50 [mg/ml] Total IgG >10.0 9.95
IC50 [mg/ml] 95 % CI ND 7.625–12.98
IC50 [µg/ml] PfCSP_TSR-specific >4.47 11.92
IC50 [µg/ml] 95 % CI ND 9.130–15.56
GIA Strain P1 P50
3D7A 7G8 V1-S 3D7A 7G8 V1-S
IC50 [mg/ml] Total IgG 27.32 31.46 23.55 8.085 8.105 9.36
IC50 [mg/ml] 95 % CI 18.89–39.50 24.45–40.49 17.92–30.94 5.812–11.25 7.120–9.227 7.672–11.420
  3D7 7G8 V1-S 3D7 7G8 V1-S
IC50 [µg/ml] PfAMA1_DiCo mix specific 160.0 184.3 137.9 120.3 120.6 139.3
IC50 [µg/ml] 95 % CI 110.6–231.3 143.2–237.1 105.0–181.2 86.49–167.3 106.0–137.2 114.2–169.8
SMFA Strain P1 P50
NF54:HSP70:GFP:luc
IC50 [mg/ml] Total IgG 0.7879 0.1427
IC50 [mg/ml] 95 % CI 0.434–1.43 0.09459–0.2153
IC50 [µg/ml] Pfs25-specific 1.409 1.049
IC50 [µg/ml] 95 % CI 0.6935–2.862 0.6952–1.583