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Table 1 Associations between Vgsc-L1014S genotype and three phenotypes in Anopheles gambiae s.s. from Tanzania

From: A significant association between deltamethrin resistance, Plasmodium falciparum infection and the Vgsc-1014S resistance mutation in Anopheles gambiae highlights the epidemiological importance of resistance markers

Phenotype N Vgsc-L1014S genotype Test statistic p value
Leu/Leu Ser/Leu Ser/Ser
Deltamethrin resistant 127 31 55 41 O.R = 1.65a p < 0.001
Deltamethrin susceptible 399 138 190 71 χ2 = 13.0b p = 0.002
Percentage resistant   18.1 % 22.4 % 36.6 % χ2 = 11.2c P < 0.001
P. falciparum positive 22 4 9 9 O.R = 2.03a p = 0.029
P. falciparum negative 504 165 236 103 Exactd p = 0.072
Percentage Pf. positive   2.4 % 3.7 % 8.0 % χ2 = 4.94c p = 0.026
Human positive 355 94 189 72 O.R = 1.26a p = 0.599
Bovine positive 17 6 8 3 Exactd p = 0.756
Percentage human positive   94 % 95.9 % 96.0 % χ2 = 1.60c p = 0.205
  1. Leucine (Leu) is the wildtype allele and Serine (Ser) the mutated resistance associated allele
  2. aOdds ratio effect size was calculated based upon allelic data
  3. bTest statistic and p value from a χ2 based on genotype frequencies
  4. cTest statistic and p value from a χ2 test of trend
  5. dA Fisher’s exact test was applied as one or more expected values <5