Plasmodium vivax infection: a major determinant of severe anaemia in infancy

Malaria Journal

Table 3 Multiple linear regression showing the effect of Plasmodium parasitaemia on mean haemoglobin concentration (g/dL)

	<1 year^a		1–5 years^a		5–15 years^a		>15 years^b		All^c
	Coef (95 % CI)	p	Coef (95 % CI)	p	Coef (95 % CI)	p	Coef (95 % CI)	p	Coef (95 % CI)	p
Malaria
Negative	0		0		0		0		0
All species	−1.35 (−2.24, −0.46)	0.003	−1.27 (−1.65, −0.89)	<0.001	−1.08 (−1.45, −0.70)	<0.001	−1.08 (−1.36, −0.80)	<0.001	−0.97 (−1.18, −0.77)	<0.001
P. falciparum	−0.66 (−2.18, 0.86)	0.4	−1.60 (−2.07, −1.12)	<0.001	−1.40 (−1.90, −0.89)	<0.001	−1.27 (−1.60, −0.94)	<0.001	−1.16 (−1.41, −0.91)	<0.001
P. vivax	−1.93 (−2.89, −0.96)	<0.001	−0.83 (−1.33, −0.33)	0.001	−0.38 (−0.91, 0.14)	0.2	−0.78 (−1.23, −0.32)	0.001	−0.66 (−0.96, −0.35	<0.001
Mixed	1.60 (1.01,2.19)	<0.001	−1.87 (−2.88, −0.85)	<0.001	−1.82 (−2.39, −1.26)	<0.001	−1.14 (−2.04, −0.25)	0.01	−1.25 (−1.80, −0.71)	<0.001

Coef coefficient, 95 % CI 95 % confidence interval
^aModels also include gender, ethnicity (non-Papuan, Highland Papuan, Lowland Papuan) and weight for age/gender/ethnicity (<mean, ≥mean)
^bModels also include gender, ethnicity (non-Papuan, Highland Papuan, Lowland Papuan) and weight for age/gender/ethnicity (<mean, ≥mean) and pregnancy status
^cModel also includes age (as a continuous variable) by gender/pregnancy status, ethnicity (non-Papuan, Highland Papuan, Lowland Papuan) and weight for age/gender/ethnicity (<mean, ≥mean)

ISSN: 1475-2875