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Table 1 Median concentrations with 25 and 75 % quartiles indicated for blood parasitaemia and eight soluble markers quantified in the plasma of children with different clinical conditions

From: Plasma levels of eight different mediators and their potential as biomarkers of various clinical malaria conditions in African children

  Mean ages (in years) Parasitaemia levels Neopterin (ng/ml) SCD163 (ng/ml) suPAR (ng/ml) PTX3 (ng/ml) sCD14 (ng/ml) Fractalkine (pg/ml) sTREM-1 (ng/ml) MIG (ng/ml)
CTS   0 1.93 [1.23–2.61] 236.6 [149.9–327.7] 3.95 [3.26–5.40] 3.21 [2.17–9.37] 2173 [1355–2945] 77.8 [65.5–111.0] 0.45 [0.27–50.2] 1.11 [0.59–1.53]
80 AM 6.3 ± 1.1 765 [58–1614] 3.99 [2.68–4.35] 514.2 [369.30–810.5] 3.72 [3.36–4.35] 0.26 [0.18–1.98] 4245 [2888–6820] 145.8 [109.4–158.0] 0.27 [0.26–0.29] 1.52 [1.41–1.60]
69 UM 2.9 ± 1.7 58,322 [20,656–113,071] 2.56 [2.15–2.98] 529.4 [371.5–910.4] 6.56 [5.58–7.57] 22.92 [8.68–47.40] 11,666 [6918–17,810] 104.3 [93.2–135.2] 0.32 [0.29–0.37] 1.49 [1.40–1.60]
39 UM + 28D 3.1 ± 1.3 0 2.47 [1.10–2.96] 228.5 [185.3–287.3] 6.45 [5.51–7.09] 3.95 [2.12–7.58] 1182 [909–1558] 21.7 [17.6–24.2] 0.39 [0.35–0.45) 0.61 [0.40–0.92]
41 SM 3.0 ± 3.1 14,008 [2317–97,928] 8.63 [8.30–9.03] 385.5 [284.6–503.5] 7.85 [6.07–9.36] 13.69 [5.27–25.27] 2970 [2079–6715] 15.3 [14.4–16.0] 0.52 [0.47–0.60] 1.81 [0.78–3.03]
25 CM 2.4 ± 2.8 100,001 [2062–201,952] 8.20 [7.69–8.83] 360.6 [252.7–470.9] 7.98 [6.93–11.69] 22.20 [8.04–35.12] 1998 [1444–3266] 15.6 [15.0–16.8] 0.50 [0.44–0.58] 2.37 [1.18–3.39]