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Table 1 Characteristics: weight, BSA, CQ real-dose, CQ theoretical dose, and blood concentrations of CQ on day 7 of follow-up in each group

From: Evaluation of the paediatric dose of chloroquine in the treatment of Plasmodium vivax malaria

Age group (years) Number records Weight (kg) BSAa (m2) CQ real doseb (mg) CQ theoretical dosec (m2) CQD7d (ng/ml)
5–9 10 21.15 (SD 5.02) 0.83 (SD 0.13) 536.50 (SD 120.69) 717.71 (SD 112.48) 235.47 (SD 69.92)
10–14 14 42.92 (SD 9.02) 1.33 (SD 0.18) 1085.50 (SD 231.58) 1156.80 (SD 156.32) 308.20 (SD 89.69)
15–24 36 61.42 (SD 9.48) 1.68 (SD 0.15) 1542.81 (SD 239.85) 1458.84 (SD 133.87) 342.72 (SD 165.28)
25–34 14 62.12 (SD 12.60) 1.68 (SD 0.20) 1562.29 (SD 322.06) 1460.28 (SD 174.16) 455.35 (SD 137.86)
35–44 11 71.32 (SD 12.94) 1.83 (SD 0.19) 1782.82 (SD 323.69) 1589.72 (SD 162.42) 395.02 (SD 199.02)
45–54 6 64.67 (SD 8.74) 1.74 (SD 0.13) 1604.08 (SD 238.12) 1510.06 (SD 115.54) 384.57 (SD 51.47)
55–65 4 69.75 (SD 13.60) 1.80 (SD 0.21) 1745.00 (SD 342.08) 1564.96 (SD 183.79) 391.20 (SD 94.90)
  1. CQ chloroquine, DCQ desethylchloroquine, SD standard deviation
  2. aBSA in m2 = body surface area calculated using the Boyd formula
  3. BSA (m2) = 0.0003207 × height (cm) 0.3 × weight (g) 0.7285 – [0.0188 × log (weight)]
  4. bCQ real dose: CQ taken in mg/kg/weight
  5. cCQ theoretical dose: CQ dose according to: (BSA/1.73)*1500 (adult dose)
  6. dCQD7: CQ + DCQ on day 7 of follow-up