Fig. 7
Plasmodium berghei ANKA infection induces increased airway reactivity that is ameliorated in αDβ2-deficient mice. Infected αDβ2-deficient and wild type mice were studied 7 days after infection. Uninfected α −/−D and α +/+D animals were also studied as controls. Airway hyperreactivity was evaluated by challenge of the animals with aerosolized phosphate buffered saline (PBS) followed by methacholine (25 mg/mL in PBS) and is expressed as average enhanced pause (Penh). Each bar represents determinations in 10 animals (mean ± SEM).#P ≤ 0.05 compared to the respective control group; *P ≤ 0.05 compared to infected α +/+D mice