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Table 2 The haplotype frequency estimations for real data set (Swiss TPH), n = 82 individual

From: Markov chain Monte Carlo and expectation maximization approaches for estimation of haplotype frequencies for multiply infected human blood samples

SNP 1 SNP 2 MHF R-EM Bayesian EM MCMC
1 1 0.928 (0.892–0.955) 0.914 (0.858–0.970) 0.936 (0.907–0.960) 0.908 (0.821–0.961) 0.914 (0.828–0.965)
1 2 0.011 (0.002–0.030) 0.016 (0.000–0.041) 0.017 (0.006–0.037) 0.013 (0.000–0.070) 0.021 (0.002–0.083)
2 1 0.004 (0.000–0.017) 0.005 (0.000–0.018) 0.007 (0.001–0.017) 0.009 (0.000–0.064) 0.008 (0.000–0.061)
2 2 0.057 (0.033–0.089) 0.065 (0.008–0.121) 0.038 (0.017–0.064) 0.069 (0.024–0.150) 0.058 (0.017–0.135)
  1. SNP 1 = wildtype alone, 2 = mutant alone, MHF MalHaploFreq, R-EM malaria.em, Bayesian Bayesian statistic, EM EM algorithm, MCMC Markov chain Monte Carlo