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Table 3 Performance RDT and microscopy in mothers and newborns relative to qPCR as gold standard

From: Prevalence and diagnostics of congenital malaria in rural Burundi, a cross-sectional study

  SD bioline HRPII Carestart pan-pLDH Smear
Sensitivity
Specificity 99.3 % (95 % CI 97.6–99.8) 100 % (95 % CI 98.3–100) 100 % 95 % CI 98.8–100)
PPV 0.0 % (95 CI 0.0–84.2)
NPV 100 % (95 % CI 98.7–100) 100 % (95 % CI 98.3–100) 100 % (95 % CI 98.8–100)
  1. Kirundo and Mukenke hospitals, Burundi (March–April 2014)
  2. PPV positive predicted value, NPV negative predicted value, CI confidence interval, SD standard diagnostics, HRPII histidine rich protein, pLDH parasite lactate dehydrogenase