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Table 2 Cytokine concentrations in culture supernatants following in vitro stimulation of PBMC

From: Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

 

IL-10

IFN-γ

TNF

IL-13

Inclusion (n = 130)a

 PHA

643 (216–1291)

4807 (1759–9021)

8567 (5081–14,620)

684 (291–1205)

 DBL-5

341 (0.06–847)

0.4 (0.4–259)

3710 (1643–6872)

0.3 (0.3–13)

Delivery (n = 109)a

 PHA

233 (0.06–1261)b

1303 (332–4326)b

6279 (3404–9470)b

364 (65–757)b

 DBL-5

195 (0.06–712)

0.4 (0.4–0.4)

2568 (1521–4981)b

0.3 (0.3–0.3)

  1. Values are median concentrations (IQR) in pg/ml
  2. aNumbers are reduced due to insufficient quantities of PBMC to perform all assays
  3. bCytokine concentration significantly lower than corresponding concentration in supernatants of PBMC at inclusion (p < 0.05 in all cases)
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Malaria Journal

ISSN: 1475-2875

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