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Table 2 Cytokine concentrations in culture supernatants following in vitro stimulation of PBMC

From: Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

  IL-10 IFN-γ TNF IL-13
Inclusion (n = 130)a
 PHA 643 (216–1291) 4807 (1759–9021) 8567 (5081–14,620) 684 (291–1205)
 DBL-5 341 (0.06–847) 0.4 (0.4–259) 3710 (1643–6872) 0.3 (0.3–13)
Delivery (n = 109)a
 PHA 233 (0.06–1261)b 1303 (332–4326)b 6279 (3404–9470)b 364 (65–757)b
 DBL-5 195 (0.06–712) 0.4 (0.4–0.4) 2568 (1521–4981)b 0.3 (0.3–0.3)
  1. Values are median concentrations (IQR) in pg/ml
  2. aNumbers are reduced due to insufficient quantities of PBMC to perform all assays
  3. bCytokine concentration significantly lower than corresponding concentration in supernatants of PBMC at inclusion (p < 0.05 in all cases)