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Table 1 Notation for parameters used throughout the manuscript

From: Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

Parameter

Description

\(j \,=\, 1,\ldots , M\)

Index over number of SNPs, M

\(i\,=\, 1,\ldots , N\)

Index over number of samples, N

\(r_{ij}, \ n_{ij}\)

Reference/non-reference read count data in sample i at variant j

\(d_{ij}\,=\, (r_{ij},n_{ij})\)

Read count data in sample i at variant j

\(p_j\) (\(\widehat{p}_j\))

Population-level non-reference allele frequency for SNP j (estimate)

\(p_{ij}\),\((\widehat{p}_{ij})\)

Within-sample non-reference allele frequency for SNP j in sample i (estimate)

\(f_i\)

Inbreeding coefficient for sample i

\(H_o(b,i)\)

Observed heterozygosity for sample i in bin b

\(H_e(b)\)

Expected heterozygosity for bin b

\(\widehat{f}^{*}_i\)

Estimator of \(f_i\) by method \(*\).

\(\ {f}, \ {p}\)

Vector of \(f_i\) and \(p_j\)’s in Bayesian model