Variables | Study sites | Total | |||
---|---|---|---|---|---|
Jhabua (MP) | Anuppur (MP) | Bastar (CG) | Simdega (JH) | ||
PCR unadjusted | |||||
Early treatment failure | 0 | 0 | 0 | 0 | 0 |
Late clinical failure | 0 | 0 | 3 | 0 | 3 |
Late parasitological failure | 0 | 0 | 4 | 0 | 4 |
Adequate clinical and parasitological response (%) | 80 (100 %) | 75 (100) | 86 (92.5) | 88 (100) | 329 (97.9) |
PCR adjusted | |||||
Early treatment failure | 0 | 0 | 0 | 0 | 0 |
Late clinical failure | 0 | 0 | 1 | 0 | 1 |
Late parasitological failure | 0 | 0 | 2 | 0 | 2 |
Adequate clinical and parasitological response (%) | 80 | 75 | 86 (95.6) | 88 (100) | 329 (99.1) |
Pf recrudescence | 0 | 0 | 2 | 0 | 2 |
Pf re-infection | 0 | 0 | 3 | 0 | 3 |
Mixed with Pf recrudescence | 0 | 0 | 1 | 0 | 1 |
PCR negative (unknown) | 0 | 0 | 1 | 0 | 1 |
Fever clearance time (hours) | |||||
Mean | 27.4 | 24.0 | 26.1 | 28.8 | 27.7 |
sd | 8.4 | 0.0 | 6.8 | 9.7 | 8.1 |
Min | 24 | 24 | 24 | 24 | 24 |
Max | 48 | 24 | 48 | 48 | 48 |
Parasite clearance time (hours) | |||||
Mean | 25.5 | 31.3 | 32.9 | 30.0 | 30.1 |
sd | 5.8 | 12.7 | 12.1 | 10.5 | 10.9 |
Min | 24 | 24 | 24 | 24 | 24 |
Max | 48 | 48 | 72 | 48 | 72 |