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Table 2 Treatment outcomes by day 28, fever and parasite clearance times with AL by study site

From: Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria from three highly malarious states in India

Variables Study sites Total
Jhabua (MP) Anuppur (MP) Bastar (CG) Simdega (JH)
PCR unadjusted
 Early treatment failure 0 0 0 0 0
 Late clinical failure 0 0 3 0 3
 Late parasitological failure 0 0 4 0 4
 Adequate clinical and parasitological response (%) 80 (100 %) 75 (100) 86 (92.5) 88 (100) 329 (97.9)
PCR adjusted
 Early treatment failure 0 0 0 0 0
 Late clinical failure 0 0 1 0 1
 Late parasitological failure 0 0 2 0 2
 Adequate clinical and parasitological response (%) 80 75 86 (95.6) 88 (100) 329 (99.1)
 Pf recrudescence 0 0 2 0 2
 Pf re-infection 0 0 3 0 3
 Mixed with Pf recrudescence 0 0 1 0 1
 PCR negative (unknown) 0 0 1 0 1
Fever clearance time (hours)
 Mean 27.4 24.0 26.1 28.8 27.7
 sd 8.4 0.0 6.8 9.7 8.1
 Min 24 24 24 24 24
 Max 48 24 48 48 48
Parasite clearance time (hours)
 Mean 25.5 31.3 32.9 30.0 30.1
 sd 5.8 12.7 12.1 10.5 10.9
 Min 24 24 24 24 24
 Max 48 48 72 48 72