Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

Kerkhof, Karen; Sluydts, Vincent; Heng, Somony; Kim, Saorin; Pareyn, Myrthe; Willen, Laura; Canier, Lydie; Sovannaroth, Siv; Ménard, Didier; Sochantha, Tho; Coosemans, Marc; Durnez, Lies

doi:10.1186/s12936-016-1558-1

Table 2 Spatial malaria pockets with higher level of antibodies against Plasmodium falciparum and Plasmodium vivax antigens detected by SaTScan v9.4.2 in Ratanakiri, Cambodia

From: Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

Antigens	Malaria pockets	Communities (out of 98)	Year	Total # persons tested per Ag	# of persons per pocket	% of people living in pocket	Radius (km)	Mean ln-MFI inside pocket	Mean ln-MFI outside pocket	Median age inside pocket	Median age outside pocket	Log likely-hood ratio	p-value
CSP	3	17	Nov 2012	3067	540	17.6	15.15	5.69	5.37	20	18	12.88	0.001
		1			18	0.6	0	6.84	5.42	16	18	10.54	0.002
		1			23	0.7	0^a	6.53	5.43	20	18	8.15	0.018
	4	12	Nov 2013	2880	335	11.6	12.46	5.77	5.41	16.5	18	11.67	0.001
		1			11	0.4	0^a	6.95	5.45	25	18	7.81	0.018
		1			20	0.7	0^a	6.54	5.45	16	18	7.48	0.026
		1			5	0.2	0^a	7.59	5.45	20	20	7.20	0.034
Pf.MSP1.19	4	19	Nov 2012	2921	563	19.3	23.18	5.46	5.21	20	18	91.87	0.001
		3			88	3.0	4.95	5.64	5.28	22	18	11.59	0.001
		5			163	5.6	5.97	5.53	5.28	15	18	10.05	0.001
		3			84	2.9	6.16	5.58	5.29	18	18	7.68	0.018
	4	19	Nov 2013	2757	549	19.9	27.49	5.68	5.31	16	19	60.45	0.001
		6			162	5.9	6.44	5.69	5.37	18	18	16.10	0.001
		1			26	0.9	0^a	6.05	5.38	26	18	11.23	0.001
		1			32	1.2	0^a	5.88	5.38	23	18	7.83	0.017
Pf.GLURP.R2	4	18	Nov 2012	3142	601	19.1	23.79	7.18	6.60	19	18	26.52	0.001
		2			59	1.9	2.90	8.01	6.69	20	18	16.77	0.001
		1			26	0.8	0^a	8.35	6.70	16	18	11.49	0.002
		1			37	1.2	0^a	7.89	6.70	14	18	8.50	0.009
	6	6	Nov 2013	2953	177	6.0	15.15	7.32	6.54	19	18	19.29	0.001
		1			40	1.4	0^a	7.87	6.57	19	18	12.90	0.002
		2			44	1.5	1.92	7.60	6.57	20	18	8.87	0.010
		5			166	5.6	5.74	7.07	6.56	19	18	7.93	0.020
		2			68	2.3	5.97	7.33	6.57	18	18	7.33	0.032
		1			20	0.7	0^a	7.97	6.57	13	18	7.33	0.032
PvAMA1	4	8	Nov 2012	3030	264	8.7	16.45	6.64	6.20	20	18	32.10	0.001
		1			21	0.7	0^a	7.61	6.23	16	18	27.25	0.001
		7			200	6.6	10.67	6.52	6.21	18.5	18	11.74	0.001
		3			56	1.8	7.00	6.70	6.23	20	18	8.35	0.025
	2	12	Nov 2013	2801	324	11.6	12.46	6.66	6.25	16.5	18	36.73	0.001
	2	6	Nov 2013	2801	182	6.5	15.15	6.64	6.28	19	18	16.39	0.001
Pv.MSP1.19	3	19	Nov 2012	2915	564	19.3	23.18	5.64	5.24	20	18	74.18	0.001
		1			12	0.4	0^a	6.41	5.31	16	18	14.45	0.001
		1			30	1.0	0^a	5.99	5.31	13	18	13.95	0.001
	4	19	Nov 2013	2762	547	19.8	27.49	5.69	5.35	16	19	48.55	0.001
		6			161	5.8	6.44	5.71	5.40	18	18	13.32	0.001
		1			34	1.2	0^a	5.94	5.41	23	18	8.54	0.012
		1			27	0.97	0^a	5.96	5.41	26	18	7.30	0.029

The MFI values inside and outside the pockets are based on the natural logarithm
^aA single village was selected as an area with a higher risk to Plasmodium infection, and therefore showing a radius of 0 km

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