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Table 2 Characteristics of children with severe malaria from Yaoundé city

From: Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers

  Healthy malaria negative (HMN) Uncomplicated malaria (UM) Cerebral malaria (CM) Severe malaria anemia (SMA) Others severe forms (OSF)
Total number of children 42 41 15 35 27
Average age in years (mean ± SD) 3.3 ± 2.2 3.3 ± 2.4 2.8 ± 1.7 1.6 ± 1.4 2.4 ± 1.8
Number males (percent) 20 (48%) 25 (61%) 8 (53%) 16 (46%) 12 (44%)
Malaria by blood smear positive (percent)a 0 100% 100% 100% 100%
Malaria parasitaemia (parasites per µL of blood, median, IQR) 53,225 (4098, 113,767) 570,725 (9752, 1,158,750) 23,792 (2842, 143,213) 281,168 (98,638, 885,063)
Hemoglobin levels in g/dL (mean ± SD) 12 ± 2 10 ± 2 6 ± 5 4 ± 2 8 ± 3
Anemia (number, %)b 14 (33%) 37 (74%) 13 (90%) 35 (100%) 26 (97%)
  1. Additional clinical characteristics for this cohort have been reported previously by Tchinda et al. [39]
  2. aBlood smears were tested by microscopy for presence of P. falciparum, P. ovale, and P. malariae. Only P. falciparum was detected
  3. bCut-offs for anemia: children 0–5 years <11 g/dL