Fig. 6From: In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisininParasitaemia inhibition and survival of mice treated with a combination of 21A and dihydro-artemisinin. Five BALB/c mice per group were infected with P. berghei ANKA. The mice were treated with three daily doses of 100 mg/kg 21A, 10 mg/kg DHA, a combination of 100 mg/kg 21A and 10 mg/kg DHA starting at day-3 post infection. The negative control mice were given three doses of 10% DMSO. a Per cent parasitaemia. The graph is the mean parasitaemia and standard error of the mean (SEM) of five mice in a group, and b Kaplan–Meier survival plot of mice treated with 21A, DHA, and a combination of 21A and DHABack to article page