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Table 3 Prevalence of amino acid substitutions in the putative drug-resistance related genes in Plasmodium falciparum isolates collected before artemether–lumefantrine treatment

From: Absence of in vivo selection for K13 mutations after artemether–lumefantrine treatment in Uganda

Gene Amino acid position Genotypes
Wild type (n, %) Mutant (n, %) Mixed (n, %)
Pfkelch13   141 (98.6) 2 (1.4) A578S 0
fd D193Y 127 (100) 0 0
mdr2 T484I 126 (100) 0 0
arps10 V127M 127 (100) 0 0
pph V1157 122 (100) 0 0
pibp C1484F 127 (100) 0 0
Pfcrt K76T 98 (68.1) 42 (29.2) 4 (2.7)
  I356T 122 (97.6) 0 3 (2.4)
Pfmdr1 N86Y 141 (98.0) 3 (2.1) 0
  Y184F 115 (80.4) 14 (9.8) 14 (9.8)
  S1034C 143 (98.6) 2 (1.4) 0
  N1042D 145 (100) 0 0
  D1246Y 134 (93.7) 9 (6.0) 0