|
Codon
|
Mutation
|
Urban area n = 102 N (%)
|
Rural area n = 142 N (%)
|
p value
|
Total prevalence n = 244 N (%)
|
95% CI
|
|---|
|
pfdhfr
|
|
pfdhfr N51I
|
51I
|
99 (97)
|
141 (99)
|
0.174
|
240 (98)
|
96.24 to 97.76
|
|
pfdhfr C59R
|
59R
|
64 (63)
|
113 (79)
|
0.003
|
177 (72)
|
66.37 to 77.63
|
|
pfdhfr S108N
|
108N
|
101 (99)
|
142 (100)
|
0.209
|
243 (99)
|
97.75 to 100.25
|
|
pfdhfr I164L
|
164L
|
0
|
2 (1.4)
|
0.337
|
2 (0.8)
|
−0.25 to 2.25
|
|
pfdhps
|
|
pfdhps S436A
|
436A
|
16 (31)
|
26 (18)
|
0.592
|
42 (17)
|
12.29 to 21.71
|
|
pfdhps A437G
|
437G
|
94 (92)
|
126 (89)
|
0.375
|
220 (90)
|
86.24 to 93.76
|
|
pfdhps K540E
|
540E
|
9 (9)
|
33 (23)
|
0.003
|
42 (17)
|
12.29 to 21.71
|
|
pfdhps A581G
|
581G
|
15 (15)
|
9 (6)
|
0.039
|
24 (10)
|
6.24 to 13.76
|
|
pfmdr1
|
|
Pfmdr1 N86Y
|
86Y
|
68 (67)
|
104 (73)
|
0.266
|
172 (70)
|
64.25 to 75.75
|
|
Pfmdr1 D1246Y
|
1246Y
|
2 (2)
|
7 (5)
|
0.224
|
9 (4)
|
1.54 to 6.46
|
|
pfcrt
|
|
pfcrt K76T
|
76T
|
28 (27)
|
46 (32)
|
0.407
|
74 (30)
|
24.25 to 35.75
|
- It shows the prevalence of each point of mutation (SNPs) in each gene of P. falciparum studied, in urban and rural settings
- ≤0.05 is taken as significance value
