Table 1 SNPs of each gene by area
Codon | Mutation | Urban area n = 102 N (%) | Rural area n = 142 N (%) | p value | Total prevalence n = 244 N (%) | 95% CI |
|---|---|---|---|---|---|---|
pfdhfr | ||||||
pfdhfr N51I | 51I | 99 (97) | 141 (99) | 0.174 | 240 (98) | 96.24 to 97.76 |
pfdhfr C59R | 59R | 64 (63) | 113 (79) | 0.003 | 177 (72) | 66.37 to 77.63 |
pfdhfr S108N | 108N | 101 (99) | 142 (100) | 0.209 | 243 (99) | 97.75 to 100.25 |
pfdhfr I164L | 164L | 0 | 2 (1.4) | 0.337 | 2 (0.8) | −0.25 to 2.25 |
pfdhps | ||||||
pfdhps S436A | 436A | 16 (31) | 26 (18) | 0.592 | 42 (17) | 12.29 to 21.71 |
pfdhps A437G | 437G | 94 (92) | 126 (89) | 0.375 | 220 (90) | 86.24 to 93.76 |
pfdhps K540E | 540E | 9 (9) | 33 (23) | 0.003 | 42 (17) | 12.29 to 21.71 |
pfdhps A581G | 581G | 15 (15) | 9 (6) | 0.039 | 24 (10) | 6.24 to 13.76 |
pfmdr1 | ||||||
Pfmdr1 N86Y | 86Y | 68 (67) | 104 (73) | 0.266 | 172 (70) | 64.25 to 75.75 |
Pfmdr1 D1246Y | 1246Y | 2 (2) | 7 (5) | 0.224 | 9 (4) | 1.54 to 6.46 |
pfcrt | ||||||
pfcrt K76T | 76T | 28 (27) | 46 (32) | 0.407 | 74 (30) | 24.25 to 35.75 |