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Table 5 Doppler velocimetry measurements and associations with measuring small for gestational age at delivery, low birth weight and placental infection on histology

From: Effects of Plasmodium falciparum infection on umbilical artery resistance and intrafetal blood flow distribution: a Doppler ultrasound study from Papua New Guinea

  % (N) OR (95% CI) P aOR (95% CI)* P*
Small for gestational age (n = 50)b
 Umbilical artery resistance index >90th centile 12.0 (44/368) 1.3 (0.4–4.0) 0.65 1.2 (0.4–4.1)* 0.73
 Middle cerebral artery pulsatility index <10th centile 11.6 (34/293) 2.0 (0.7–5.4) 0.16 2.3 (0.8–6.1) 0.10
 Cerebroplacental Doppler ratio <10th centile 11.5 (28/243) 2.1 (0.8–6.0) 0.15 2.7 (1.0–7.7) 0.053
 Cerebroplacental Doppler ratio <1.0 11.5 (28/243) 1.4 (0.6–3.4) 0.48 3.3 (1.2–9.2) 0.024
Low birth weight (n = 67)c
 Umbilical artery resistance index >90th centile 16.6 (60/361) 1.3 (0.6–2.7) 0.52 1.3 (0.6–2.8) 0.56
 Middle cerebral artery pulsatility index <10th centile 17.8 (53/298) 1.9 (0.9–4.1) 0.08 2.0 (1.0–4.3) 0.07
 Cerebroplacental Doppler ratio <10th centile 17.8 (45/252) 2.8 (1.3–6.3) 0.011 2.5 (1.1–5.7) 0.033
 Cerebroplacental Doppler ratio <1.0 17.8 (45/252) 2.6 (1.3–4.9) 0.005 2.8 (1.3–6.0) 0.007
Placental malaria (n = 46)c
 Umbilical artery resistance index >90th centile 15.6 (44/281) 4.9 (2.3–10.7) <0.001 5.1 (2.3–10.9) <0.001
 Middle cerebral artery pulsatility index <10th centile 14.5 (34/234) 1.8 (0.7–5.1) 0.24 1.8 (0.6–5.0) 0.23
 Cerebroplacental Doppler ratio <10th centile 14.7 (29/197) 1.5 (0.5–5.0) 0.47 1.3 (0.4–4.6) 0.65
 Cerebroplacental Doppler ratio <1.0 14.7 (29/197) 1.8 (0.8–4.3) 0.16 1.8 (0.7–4.8) 0.26
  1. * Adjusted for fetal sex, gravidity and gestational age
  2. aN (%) represents the number of scans
  3. bN (%) represents the number of women