|
Screened, n
|
445
|
443
|
150
|
223
|
318
|
225
|
|
Enrolled, n
|
101
|
101
|
104
|
102
|
100
|
78
|
|
Lost to follow up, n (%)
|
20 (20)
|
11 (11)
|
7 (7)
|
12 (12)
|
14 (14)
|
9 (12)
|
|
Excluded, n (%)
|
8 (8)
|
5 (5)
|
4 (4)
|
6 (6)
|
10 (10)
|
13 (17)
|
|
Reached study endpoint, n (%)
|
73 (72)
|
85 (84)
|
93 (89)
|
84 (82)
|
76 (76)
|
56 (72)
|
|
Participant characteristics at baseline
|
|
Median age, years (range)
|
5.0 (0.7–12)
|
6.4 (1–12)
|
3.0 (0.6–5)
|
2.8 (0.6–5)
|
2.8 (0.5–5)
|
3.2 (0.5–5)
|
|
Median weight, kg (range)
|
16 (6–37)
|
18 (8–42)
|
13 (7–19)
|
13 (6–19)
|
12 (6–21)
|
12 (7–18)
|
|
Percent female
|
40%
|
40%
|
51%
|
53%
|
42%
|
58%
|
|
Median day 0 parasitemia, parasites/µL (range)
|
29,487 (1051–99,507)
|
20,151 (1003–92,733)
|
47,766 (2034–195,529)
|
48,049 (2003–187,777)
|
7266 (2000–180,903)
|
16,071 (2000–161,333)
|
|
Median day 0 hemoglobin, g/dL (range)
|
10.3 (5.2–13.3)
|
10.2 (5.4–13.5)
|
10.2 (5.7–13.6)
|
10.0 (6–13.3)
|
9.4 (5.1–13.5)
|
9.2 (5.5–13.6)
|
