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Table 2 Comparison of haematological indices in children with malaria across three transmission areas

From: Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria

Haematological indices

Study sites

Kruskal–Wallis

Kintampo

(N = 266)

Navrongo

(N = 144)

Accra

(N = 117)

P value

Median (IQR)

Median (IQR)

Median (IQR)

Erythrocyte indices

 RBC (103/mm3)

4.0 (3.5–4.4)

4.1 (3.6–4.5)

4.4 (4.0–4.8)

<0.001

 MCV (µm3)

78.0 (74.0–81.0)

75.0 (70.0–78.0)

73.7 (68.5–77.7)

<0.001

 MCH (pg.)

25.5 (23.6–26.7)

25.8 (23.9–27.3)

25.1 (23.1–26.9)

0.131

 MCHC (g/dL)

32.4 (31.7–33.3)

34.3 (33.5–35.2)

34.1 (33.1–35.0)

<0.001

 RDW (%)

15.1 (14.1–16.5)

16.4 (15.4–17.6)

14.7 (13.6–16.2)

<0.001

Leucocyte indices

 WBC (103/mm3)

8.5 (6.6–13.0)

8.2 (5.8–10.4)

7.5 (5.5–10.3)

0.016

 LYM (%)

30.1 (21.0–41.3)

19.4 (13.2–28.9)

18.5 (13.8–29.7)

<0.001

 MON (%)

6.8 (5.3–8.6)

5.5 (3.8–7.5)

7.1 (4.5–11.0)

<0.001

 GRA (%)

62.6 (49.5–72.6)

75.2 (64.2–83.1)

72.4 (61.6–79.7)

<0.001

Platelet indices

 PLT (103/mm3)

125.5 (87.8–182.0)

141.0 (100.0–210.3)

126.5 (78.3–210.3)

0.048

 MPV (µm3)

7.3 (6.8–8.3)

7.8 (7.3–8.3)

9.3 (8.8–10.2)

<0.001

 PDW (%)

15.1 (13.2–17.3)

14.7 (11.5–16.5)

11.9 (10.8–14.0)

<0.001

  1. Data are presented as medians (first quartile-third quartile)
  2. Relative malaria transmission intensities as measured by entomological inoculation rates in the areas are in the order Kintampo > Navrongo > Accra